Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | the enzyme can be stimulated by human AP endonuclease 1 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q13569 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
8-(hydroxymethyl)-3,N4-ethenocytosine-mismatched double-stranded DNA + H2O | TDG is able to excise the 8-(hydroxymethyl)-3,N4-ethenocytosine from DNA. TDG activity displays a marked preference of guanine opposite to 8-(hydroxymethyl)-3,N4-ethenocytosine over any other bases. TDG does not show any detectable activity toward 3,N4-ethanocytosine when placed in various neighboring sequences, including the 5'-CpG site | Homo sapiens | 8-(hydroxymethyl)-3,N4-ethenocytosine + double-stranded DNA with abasic site | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TDG | - |
Homo sapiens |
thymine-DNA glycosylase | - |
Homo sapiens |